HCSGD entry for CIT
1. General information
| Official gene symbol | CIT |
|---|---|
| Entrez ID | 11113 |
| Gene full name | citron (rho-interacting, serine/threonine kinase 21) |
| Other gene symbols | CRIK STK21 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000070 | Mitotic sister chromatid segregation | IEA | biological_process |
| GO:0000086 | G2/M transition of mitotic cell cycle | IEA | biological_process |
| GO:0000910 | Cytokinesis | IMP | biological_process |
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0004674 | Protein serine/threonine kinase activity | IEA ISS | molecular_function |
| GO:0005083 | Small GTPase regulator activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005773 | Vacuole | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007030 | Golgi organization | IEA | biological_process |
| GO:0007067 | Mitosis | ISS | biological_process |
| GO:0007091 | Metaphase/anaphase transition of mitotic cell cycle | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008064 | Regulation of actin polymerization or depolymerization | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IEA | cellular_component |
| GO:0016358 | Dendrite development | IEA | biological_process |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0031985 | Golgi cisterna | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048699 | Generation of neurons | ISS | biological_process |
| GO:0050774 | Negative regulation of dendrite morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9999213176 | 0.0005906766 | 0.9999902473 | 0.0455929619 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -1.0087177156 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024814 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026796 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038779 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040664 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-29b-3p | MIMAT0000100 | MIRT048374 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048952 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
