HCSGD entry for FICD
1. General information
| Official gene symbol | FICD |
|---|---|
| Entrez ID | 11153 |
| Gene full name | FIC domain containing |
| Other gene symbols | HIP13 HYPE UNQ3041 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018117 | Protein adenylylation | IDA | biological_process |
| GO:0034259 | Negative regulation of Rho GTPase activity | TAS | biological_process |
| GO:0070733 | Protein adenylyltransferase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0317666654 | 0.9398688994 | 0.4114814961 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4214533889 |
| GSE13712_SHEAR | Down | -0.5962793748 |
| GSE13712_STATIC | Down | -0.2386347843 |
| GSE19018 | Down | -0.0379217071 |
| GSE19899_A1 | Down | -0.0584366265 |
| GSE19899_A2 | Up | 0.9100026125 |
| PubMed_21979375_A1 | Up | 0.2605096612 |
| PubMed_21979375_A2 | Up | 0.2494282967 |
| GSE35957 | Down | -0.2552472866 |
| GSE36640 | Up | 0.6592096549 |
| GSE54402 | Up | 0.2240105365 |
| GSE9593 | Up | 0.4098456651 |
| GSE43922 | Up | 0.7564950322 |
| GSE24585 | Up | 0.3787688532 |
| GSE37065 | Up | 0.2777742723 |
| GSE28863_A1 | Down | -0.0467039433 |
| GSE28863_A2 | Up | 0.1620969162 |
| GSE28863_A3 | Up | 0.0996062844 |
| GSE28863_A4 | Up | 0.0558094676 |
| GSE48662 | Up | 0.0414519821 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018709 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029945 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26166298 | Here, we examined whether a biomarker-based frailty index (FI-B) allowed examination of their collective effect in predicting mortality compared with individual biomarkers, a clinical deficits frailty index (FI-CD), and the Fried frailty phenotype |
| 26166298 | The ROC analysis showed moderate discriminative ability for 7-year mortality (AUC for FI-CD = 0 |
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