HCSGD entry for BAZ2A
1. General information
| Official gene symbol | BAZ2A |
|---|---|
| Entrez ID | 11176 |
| Gene full name | bromodomain adjacent to zinc finger domain, 2A |
| Other gene symbols | TIP5 WALp3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000183 | Chromatin silencing at rDNA | IEA ISS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005677 | Chromatin silencing complex | ISS | cellular_component |
| GO:0005730 | Nucleolus | IEA ISS | cellular_component |
| GO:0006306 | DNA methylation | ISS | biological_process |
| GO:0006338 | Chromatin remodeling | NAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | NAS | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016575 | Histone deacetylation | ISS | biological_process |
| GO:0016922 | Ligand-dependent nuclear receptor binding | NAS | molecular_function |
| GO:0033553 | RDNA heterochromatin | ISS | cellular_component |
| GO:0034770 | Histone H4-K20 methylation | IEA | biological_process |
| GO:0051567 | Histone H3-K9 methylation | IEA | biological_process |
| GO:0070577 | Histone acetyl-lysine binding | ISS | molecular_function |
| GO:0070869 | Heterochromatin assembly involved in chromatin silencing | IEA | biological_process |
| GO:0070933 | Histone H4 deacetylation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0192714411 | 0.9851677406 | 0.3381279813 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0083073812 |
| GSE13712_SHEAR | Up | 0.0843413854 |
| GSE13712_STATIC | Down | -0.0684450049 |
| GSE19018 | Up | 0.2246745250 |
| GSE19899_A1 | Up | 0.1283993014 |
| GSE19899_A2 | Up | 0.4589021871 |
| PubMed_21979375_A1 | Down | -0.0709621916 |
| PubMed_21979375_A2 | Up | 0.6204845592 |
| GSE35957 | Down | -0.1317727953 |
| GSE36640 | Up | 0.4700125755 |
| GSE54402 | Up | 0.0447966054 |
| GSE9593 | Down | -0.0537918820 |
| GSE43922 | Up | 0.6396716720 |
| GSE24585 | Up | 0.3039830146 |
| GSE37065 | Up | 0.2598555330 |
| GSE28863_A1 | Up | 0.8727266508 |
| GSE28863_A2 | Up | 0.8393107792 |
| GSE28863_A3 | Down | -0.0609817702 |
| GSE28863_A4 | Up | 0.0461109842 |
| GSE48662 | Up | 0.4159525356 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035918 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037164 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-671-5p | MIMAT0003880 | MIRT039284 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039339 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042071 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043809 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046228 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048749 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050400 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051012 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051904 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052394 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26505814 | Depletion of the nucleolar transcription repressor factor TIP5 also promoted escape from senescence |
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