HCSGD entry for LZTS1

1. General information

Official gene symbolLZTS1
Entrez ID11178
Gene full nameleucine zipper, putative tumor suppressor 1
Other gene symbolsF37 FEZ1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingNASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006351Transcription, DNA-templatedNASbiological_process
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0006385Transcription elongation from RNA polymerase III promoterTASbiological_process
GO:0006386Termination of RNA polymerase III transcriptionTASbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016242Negative regulation of macroautophagyIMPbiological_process
GO:0016324Apical plasma membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0043197Dendritic spineIEAcellular_component
GO:0043198Dendritic shaftIEAcellular_component
GO:0044297Cell bodyIEAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0048814Regulation of dendrite morphogenesisIEAbiological_process
GO:2001141Regulation of RNA biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97634288590.11726946540.99999024730.6572933560

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0771977966
GSE13712_SHEARDown-0.0824741360
GSE13712_STATICUp0.0105535330
GSE19018Up0.0190194629
GSE19899_A1Down-0.1121461752
GSE19899_A2Down-0.5556686109
PubMed_21979375_A1Down-0.5028917456
PubMed_21979375_A2Down-0.4106302144
GSE35957Down-0.0002713346
GSE36640Down-0.5238790525
GSE54402Down-0.1500392368
GSE9593Up0.0097161912
GSE43922Up0.0545096506
GSE24585Down-0.1979769270
GSE37065Down-0.1586886175
GSE28863_A1Down-0.0808142624
GSE28863_A2Down-0.1357212284
GSE28863_A3Up0.3269040383
GSE28863_A4Up0.0014950585
GSE48662Down-0.1354149471

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.