HCSGD entry for GTF3C6
1. General information
| Official gene symbol | GTF3C6 |
|---|---|
| Entrez ID | 112495 |
| Gene full name | general transcription factor IIIC, polypeptide 6, alpha 35kDa |
| Other gene symbols | C6orf51 TFIIIC35 bA397G5.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000127 | Transcription factor TFIIIC complex | IDA | cellular_component |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006351 | Transcription, DNA-templated | IDA | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | IDA | biological_process |
| GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | IC | biological_process |
| GO:0042797 | TRNA transcription from RNA polymerase III promoter | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1898530337 | 0.4578018350 | 0.8478319817 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4791844928 |
| GSE13712_SHEAR | Up | 0.2936037176 |
| GSE13712_STATIC | Up | 0.3372457187 |
| GSE19018 | Down | -0.8100352224 |
| GSE19899_A1 | Up | 0.3764839248 |
| GSE19899_A2 | Up | 0.4086288370 |
| PubMed_21979375_A1 | Down | -0.0606165260 |
| PubMed_21979375_A2 | Up | 0.0967638500 |
| GSE35957 | Down | -0.3807598264 |
| GSE36640 | Up | 0.0124682806 |
| GSE54402 | Up | 0.2817856572 |
| GSE9593 | Down | -0.0256694348 |
| GSE43922 | Up | 0.1476493991 |
| GSE24585 | Down | -0.2252658940 |
| GSE37065 | Down | -0.0565279997 |
| GSE28863_A1 | Down | -0.0844936355 |
| GSE28863_A2 | Down | -0.0517446344 |
| GSE28863_A3 | Up | 0.2236247769 |
| GSE28863_A4 | Down | -0.1558008847 |
| GSE48662 | Down | -0.3689735837 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022263 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023234 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT023623 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
