HCSGD entry for TP53RK
1. General information
| Official gene symbol | TP53RK |
|---|---|
| Entrez ID | 112858 |
| Gene full name | TP53 regulating kinase |
| Other gene symbols | BUD32 C20orf64 Nori-2 Nori-2p PRPK dJ101A2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002039 | P53 binding | IDA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0008033 | TRNA processing | IEA | biological_process |
| GO:0009103 | Lipopolysaccharide biosynthetic process | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0126415182 | 0.9331314692 | 0.2810282095 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5491963492 |
| GSE13712_SHEAR | Down | -0.1561883979 |
| GSE13712_STATIC | Up | 0.0502724685 |
| GSE19018 | Down | -0.6630804360 |
| GSE19899_A1 | Up | 0.6406978541 |
| GSE19899_A2 | Up | 1.2432708824 |
| PubMed_21979375_A1 | Up | 1.1928324858 |
| PubMed_21979375_A2 | Up | 0.7167701875 |
| GSE35957 | Up | 0.0173039296 |
| GSE36640 | Up | 0.1102073558 |
| GSE54402 | Up | 0.9690004808 |
| GSE9593 | Up | 0.2643285539 |
| GSE43922 | Up | 0.6069773223 |
| GSE24585 | Down | -0.0823742499 |
| GSE37065 | Up | 0.1506111796 |
| GSE28863_A1 | Up | 0.0673804926 |
| GSE28863_A2 | Up | 0.0415474675 |
| GSE28863_A3 | Down | -0.1740457229 |
| GSE28863_A4 | Up | 0.1370635040 |
| GSE48662 | Down | -0.1684690100 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-505-5p | MIMAT0004776 | MIRT037962 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048227 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
