HCSGD entry for CHRM3

1. General information

Official gene symbolCHRM3
Entrez ID1131
Gene full namecholinergic receptor, muscarinic 3
Other gene symbolsEGBRS HM3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003056Regulation of vascular smooth muscle contractionIEAbiological_process
GO:0004435Phosphatidylinositol phospholipase C activityTASmolecular_function
GO:0004872Receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006464Cellular protein modification processTASbiological_process
GO:0006939Smooth muscle contractionIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008144Drug bindingIEAmolecular_function
GO:0008283Cell proliferationTASbiological_process
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0016907G-protein coupled acetylcholine receptor activityIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0032279Asymmetric synapseIEAcellular_component
GO:0042166Acetylcholine bindingIEAmolecular_function
GO:0043679Axon terminusIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0045987Positive regulation of smooth muscle contractionIEAbiological_process
GO:0046541Saliva secretionIEAbiological_process
GO:0050796Regulation of insulin secretionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33847202610.93281400020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0040542595
GSE13712_SHEARUp0.0956491348
GSE13712_STATICUp0.0554594771
GSE19018Down-0.0892931069
GSE19899_A1Up0.1832703053
GSE19899_A2Up0.0459020176
PubMed_21979375_A1Down-0.0553687038
PubMed_21979375_A2Down-0.0857533048
GSE35957Up0.1198367023
GSE36640Up0.0255196665
GSE54402Up0.0246693030
GSE9593Up0.0619878557
GSE43922Up0.0250314036
GSE24585Up0.3359919709
GSE37065Up0.0401053237
GSE28863_A1Down-0.1669698300
GSE28863_A2Up0.1329164475
GSE28863_A3Up0.2812453442
GSE28863_A4Up0.2382072762
GSE48662Up0.0139212335

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018504MicroarrayFunctional MTI (Weak)18185580
hsa-miR-296-3pMIMAT0004679MIRT038434CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.