HCSGD entry for GPN1
1. General information
| Official gene symbol | GPN1 |
|---|---|
| Entrez ID | 11321 |
| Gene full name | GPN-loop GTPase 1 |
| Other gene symbols | ATPBD1A MBDIN NTPBP RPAP4 XAB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0017111 | Nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5739326431 | 0.0887375670 | 0.9999902473 | 0.5649882680 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0874352276 |
| GSE13712_SHEAR | Up | 0.0482354563 |
| GSE13712_STATIC | Down | -0.0336287732 |
| GSE19018 | Down | -0.2968687999 |
| GSE19899_A1 | Down | -0.0131617695 |
| GSE19899_A2 | Down | -0.0690258450 |
| PubMed_21979375_A1 | Up | 0.8831290641 |
| PubMed_21979375_A2 | Up | 0.4119076348 |
| GSE35957 | Down | -0.3997158441 |
| GSE36640 | Down | -0.4117233184 |
| GSE54402 | Up | 0.5901569484 |
| GSE9593 | Down | -0.3032304315 |
| GSE43922 | Up | 0.0969027352 |
| GSE24585 | Down | -0.3734336876 |
| GSE37065 | Down | -0.0376679376 |
| GSE28863_A1 | Down | -0.2111801018 |
| GSE28863_A2 | Up | 0.3953530094 |
| GSE28863_A3 | Down | -0.9191723913 |
| GSE28863_A4 | Down | -0.1410255999 |
| GSE48662 | Down | -0.5958926624 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-151a-5p | MIMAT0004697 | MIRT019517 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027807 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-320a | MIMAT0000510 | MIRT044449 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052371 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
