HCSGD entry for PIK3IP1
1. General information
| Official gene symbol | PIK3IP1 |
|---|---|
| Entrez ID | 113791 |
| Gene full name | phosphoinositide-3-kinase interacting protein 1 |
| Other gene symbols | HGFL hHGFL(S) |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0014067 | Negative regulation of phosphatidylinositol 3-kinase signaling | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0036313 | Phosphatidylinositol 3-kinase catalytic subunit binding | IPI | molecular_function |
| GO:0043553 | Negative regulation of phosphatidylinositol 3-kinase activity | IDA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0141870560 | 0.3777982182 | 0.2944932965 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2144073680 |
| GSE13712_SHEAR | Down | -0.1909668739 |
| GSE13712_STATIC | Up | 0.2991953846 |
| GSE19018 | Up | 0.7613010667 |
| GSE19899_A1 | Down | -0.0730257342 |
| GSE19899_A2 | Down | -0.0317194823 |
| PubMed_21979375_A1 | Down | -0.6859376447 |
| PubMed_21979375_A2 | Down | -0.4307072994 |
| GSE35957 | Up | 1.4208223412 |
| GSE36640 | Up | 3.0251159867 |
| GSE54402 | Down | -0.2226655375 |
| GSE9593 | Up | 0.4663430491 |
| GSE43922 | Down | -0.7224703815 |
| GSE24585 | Up | 0.2792971464 |
| GSE37065 | Up | 0.1282907102 |
| GSE28863_A1 | Up | 0.1912263102 |
| GSE28863_A2 | Up | 0.8724414750 |
| GSE28863_A3 | Up | 0.0650260836 |
| GSE28863_A4 | Down | -0.1868936130 |
| GSE48662 | Up | 0.8122363630 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT020011 | Microarray | Functional MTI (Weak) | 20215506 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
