HCSGD entry for CHRNE

1. General information

Official gene symbolCHRNE
Entrez ID1145
Gene full namecholinergic receptor, nicotinic, epsilon (muscle)
Other gene symbolsACHRE CMS1D CMS1E CMS2A FCCMS SCCMS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004889Acetylcholine-activated cation-selective channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005892Acetylcholine-gated channel complexTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006812Cation transportTASbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007271Synaptic transmission, cholinergicTASbiological_process
GO:0008324Cation transmembrane transporter activityTASmolecular_function
GO:0015464Acetylcholine receptor activityTASmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63868075680.48480340030.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0819774118
GSE13712_SHEARDown-0.0638345098
GSE13712_STATICDown-0.0232446116
GSE19018Up0.1557297183
GSE19899_A1Up0.0782860826
GSE19899_A2Down-0.1897687571
PubMed_21979375_A1Up0.0546922673
PubMed_21979375_A2Down-0.3561434410
GSE35957Down-0.1409026926
GSE36640Down-0.0347662416
GSE54402Down-0.0411579487
GSE9593Down-0.2415713606
GSE43922Down-0.0091745705
GSE24585Up0.0837844555
GSE37065Up0.1410470721
GSE28863_A1Down-0.0533512049
GSE28863_A2Down-0.0819125588
GSE28863_A3Up0.3528647640
GSE28863_A4Up0.1332369452
GSE48662Up0.4335799377

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GalantamineDB00674 APRD00206 | EXPT01628

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.