HCSGD entry for PTPMT1
1. General information
| Official gene symbol | PTPMT1 |
|---|---|
| Entrez ID | 114971 |
| Gene full name | protein tyrosine phosphatase, mitochondrial 1 |
| Other gene symbols | DUSP23 MOSP PLIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004439 | Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | IBA | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IBA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IBA | biological_process |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006655 | Phosphatidylglycerol biosynthetic process | TAS | biological_process |
| GO:0008138 | Protein tyrosine/serine/threonine phosphatase activity | IBA | molecular_function |
| GO:0008962 | Phosphatidylglycerophosphatase activity | ISS | molecular_function |
| GO:0032049 | Cardiolipin biosynthetic process | ISS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0046855 | Inositol phosphate dephosphorylation | IBA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2427335398 | 0.7607031154 | 0.9299221123 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2065882397 |
| GSE13712_SHEAR | Down | -0.5107103809 |
| GSE13712_STATIC | Up | 0.4246058855 |
| GSE19018 | Down | -0.1151663564 |
| GSE19899_A1 | Up | 0.1243876299 |
| GSE19899_A2 | Up | 0.4765379097 |
| PubMed_21979375_A1 | Up | 0.2871370644 |
| PubMed_21979375_A2 | Up | 0.3911399890 |
| GSE35957 | Up | 0.0284516957 |
| GSE36640 | Up | 0.5782933187 |
| GSE54402 | Down | -0.0196651743 |
| GSE9593 | Up | 0.2382419075 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.2446280383 |
| GSE28863_A2 | Up | 0.0109824256 |
| GSE28863_A3 | Down | -0.6398139726 |
| GSE28863_A4 | Up | 0.1181647022 |
| GSE48662 | Down | -0.0995456333 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019753 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-1 | MIMAT0000416 | MIRT023582 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037666 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045130 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
