HCSGD entry for CKS2
1. General information
| Official gene symbol | CKS2 |
|---|---|
| Entrez ID | 1164 |
| Gene full name | CDC28 protein kinase regulatory subunit 2 |
| Other gene symbols | CKSHS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | TAS | biological_process |
| GO:0007049 | Cell cycle | NAS | biological_process |
| GO:0007051 | Spindle organization | NAS | biological_process |
| GO:0007127 | Meiosis I | IEA | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0016538 | Cyclin-dependent protein serine/threonine kinase regulator activity | IEA | molecular_function |
| GO:0048015 | Phosphatidylinositol-mediated signaling | NAS | biological_process |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5027592645 | 0.0031097033 | 0.9999902473 | 0.1118176230 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.0239535817 |
| GSE13712_SHEAR | Up | 0.6987818123 |
| GSE13712_STATIC | Up | 0.4248555189 |
| GSE19018 | Up | 0.3522719081 |
| GSE19899_A1 | Down | -0.2753357634 |
| GSE19899_A2 | Down | -0.8110430830 |
| PubMed_21979375_A1 | Up | 0.0691848381 |
| PubMed_21979375_A2 | Down | -0.3679775577 |
| GSE35957 | Down | -2.9399596062 |
| GSE36640 | Down | -2.1706397224 |
| GSE54402 | Down | -0.4540495731 |
| GSE9593 | Down | -0.8987922263 |
| GSE43922 | Up | 0.1281564092 |
| GSE24585 | Down | -0.5922283040 |
| GSE37065 | Down | -0.1284575452 |
| GSE28863_A1 | Up | 0.0609757846 |
| GSE28863_A2 | Up | 0.1401350566 |
| GSE28863_A3 | Down | -0.4589186846 |
| GSE28863_A4 | Up | 0.3260780496 |
| GSE48662 | Down | -1.2015222256 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022264 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052270 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
