HCSGD entry for ADD1

1. General information

Official gene symbolADD1
Entrez ID118
Gene full nameadducin 1 (alpha)
Other gene symbolsADDA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000902Cell morphogenesisIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003779Actin bindingTASmolecular_function
GO:0005198Structural molecule activityIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006884Cell volume homeostasisIEAbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006921Cellular component disassembly involved in execution phase of apoptosisTASbiological_process
GO:0006987Activation of signaling protein activity involved in unfolded protein responseTASbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0008290F-actin capping protein complexIDAcellular_component
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0020027Hemoglobin metabolic processIEAbiological_process
GO:0030036Actin cytoskeleton organizationICbiological_process
GO:0030218Erythrocyte differentiationIEAbiological_process
GO:0030507Spectrin bindingIDAmolecular_function
GO:0030837Negative regulation of actin filament polymerizationIEAbiological_process
GO:0030968Endoplasmic reticulum unfolded protein responseTASbiological_process
GO:0032092Positive regulation of protein bindingIDAbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042608T cell receptor bindingIEAmolecular_function
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043197Dendritic spineIEAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0045766Positive regulation of angiogenesisIEAbiological_process
GO:0045807Positive regulation of endocytosisIEAbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0048873Homeostasis of number of cells within a tissueIEAbiological_process
GO:0051015Actin filament bindingIDAmolecular_function
GO:0051016Barbed-end actin filament cappingIDAbiological_process
GO:0051017Actin filament bundle assemblyIDAbiological_process
GO:0071300Cellular response to retinoic acidIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21922021580.28227596980.90072671241.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0972343236
GSE13712_SHEARDown-0.3302805733
GSE13712_STATICDown-0.2466631267
GSE19018Up0.1374784501
GSE19899_A1Down-0.4574407677
GSE19899_A2Up0.1079281377
PubMed_21979375_A1Down-1.1860994631
PubMed_21979375_A2Up0.0494909444
GSE35957Up0.2220222904
GSE36640Up0.6196372929
GSE54402Down-0.3528114938
GSE9593Up0.2404526737
GSE43922Down-0.4536985685
GSE24585Up0.1960507429
GSE37065Down-0.2057644949
GSE28863_A1Up0.7435422205
GSE28863_A2Up0.4809959463
GSE28863_A3Up0.1810256284
GSE28863_A4Down-0.0523580468
GSE48662Up0.5514877187

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-24-3pMIMAT0000080MIRT030434MicroarrayFunctional MTI (Weak)19748357
hsa-miR-221-3pMIMAT0000278MIRT046898CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.