HCSGD entry for CLNS1A
1. General information
| Official gene symbol | CLNS1A |
|---|---|
| Entrez ID | 1207 |
| Gene full name | chloride channel, nucleotide-sensitive, 1A |
| Other gene symbols | CLCI CLNS1B ICln |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000387 | Spliceosomal snRNP assembly | IDA TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006821 | Chloride transport | IEA | biological_process |
| GO:0006884 | Cell volume homeostasis | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0034660 | NcRNA metabolic process | TAS | biological_process |
| GO:0034709 | Methylosome | IDA | cellular_component |
| GO:0034715 | PICln-Sm protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9101520573 | 0.2197994073 | 0.9999902473 | 0.9025491732 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0039669735 |
| GSE13712_SHEAR | Down | -0.0883588338 |
| GSE13712_STATIC | Up | 0.0623694860 |
| GSE19018 | Up | 0.1477556646 |
| GSE19899_A1 | Up | 0.0303734529 |
| GSE19899_A2 | Down | -0.0167129620 |
| PubMed_21979375_A1 | Down | -0.4611714527 |
| PubMed_21979375_A2 | Down | -0.0212849197 |
| GSE35957 | Down | -0.2267850955 |
| GSE36640 | Down | -0.1100263282 |
| GSE54402 | Down | -0.0462433955 |
| GSE9593 | Down | -0.3912738819 |
| GSE43922 | Down | -0.1233169096 |
| GSE24585 | Down | -0.4997656775 |
| GSE37065 | Up | 0.1572042929 |
| GSE28863_A1 | Up | 0.3507157584 |
| GSE28863_A2 | Down | -0.0210979960 |
| GSE28863_A3 | Down | -0.2269834699 |
| GSE28863_A4 | Up | 0.0303274950 |
| GSE48662 | Down | -0.0561801357 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031611 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048993 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
