HCSGD entry for CLTA

1. General information

Official gene symbolCLTA
Entrez ID1211
Gene full nameclathrin, light chain A
Other gene symbolsLCA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005198Structural molecule activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006886Intracellular protein transportIEAbiological_process
GO:0006892Post-Golgi vesicle-mediated transportTASbiological_process
GO:0006897EndocytosisIEAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0016023Cytoplasmic membrane-bounded vesicleISScellular_component
GO:0016192Vesicle-mediated transportIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030118Clathrin coatNAScellular_component
GO:0030130Clathrin coat of trans-Golgi network vesicleIEAcellular_component
GO:0030132Clathrin coat of coated pitIEAcellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0032050Clathrin heavy chain bindingIPImolecular_function
GO:0032588Trans-Golgi network membraneTAScellular_component
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0042277Peptide bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0071439Clathrin complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29840664110.93980700580.99725256481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3166490035
GSE13712_SHEARUp0.0041212922
GSE13712_STATICUp0.0298725805
GSE19018Down-0.1974338086
GSE19899_A1Up0.0652489484
GSE19899_A2Up0.2066254833
PubMed_21979375_A1Up0.2835098350
PubMed_21979375_A2Up0.2900850139
GSE35957Down-0.0713288863
GSE36640Down-0.0415994093
GSE54402Up0.1145267438
GSE9593Up0.2070822881
GSE43922Down-0.0394382775
GSE24585Up0.1016332999
GSE37065Up0.0629800474
GSE28863_A1Up0.0409813728
GSE28863_A2Up0.1988963772
GSE28863_A3Down-0.1068128796
GSE28863_A4Up0.2574483394
GSE48662Down-0.0675891172

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020728ProteomicsFunctional MTI (Weak)18668040
hsa-miR-124-3pMIMAT0000422MIRT022724Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029517MicroarrayFunctional MTI (Weak)19088304
hsa-miR-23b-3pMIMAT0000418MIRT046362CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.