HCSGD entry for CCR8
1. General information
| Official gene symbol | CCR8 |
|---|---|
| Entrez ID | 1237 |
| Gene full name | chemokine (C-C motif) receptor 8 |
| Other gene symbols | CC-CKR-8 CCR-8 CDw198 CKRL1 CMKBR8 CMKBRL2 CY6 GPRCY6 TER1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004950 | Chemokine receptor activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006935 | Chemotaxis | IEA | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | IEA | biological_process |
| GO:0015026 | Coreceptor activity | TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016493 | C-C chemokine receptor activity | IEA | molecular_function |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0070098 | Chemokine-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6720340907 | 0.9160232096 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0050048150 |
| GSE13712_SHEAR | Up | 0.0582275094 |
| GSE13712_STATIC | Down | -0.0158845075 |
| GSE19018 | Down | -0.1201032452 |
| GSE19899_A1 | Up | 0.1395559743 |
| GSE19899_A2 | Up | 0.2014907791 |
| PubMed_21979375_A1 | Up | 0.0272475861 |
| PubMed_21979375_A2 | Up | 0.1803658289 |
| GSE35957 | Up | 0.1759405979 |
| GSE36640 | Down | -0.0446171986 |
| GSE54402 | Up | 0.0002240836 |
| GSE9593 | Up | 0.0808738421 |
| GSE43922 | Up | 0.0127470645 |
| GSE24585 | Down | -0.0669537638 |
| GSE37065 | Up | 0.0500567160 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0026148959 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 18157152 | TER1, the RNA subunit of fission yeast telomerase |
| 18157152 | Here we report the identification and functional characterization of TER1, the telomerase RNA component from fission yeast Schizosaccharomyces pombe |
| 18157152 | Interactions between Est1 and Trt1, the two known protein components of fission yeast telomerase, were dependent on TER1, supporting its role as a scaffold for the assembly of protein subunits |
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