HCSGD entry for ADH1A

1. General information

Official gene symbolADH1A
Entrez ID124
Gene full namealcohol dehydrogenase 1A (class I), alpha polypeptide
Other gene symbolsADH1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004022Alcohol dehydrogenase (NAD) activityTASmolecular_function
GO:0004024Alcohol dehydrogenase activity, zinc-dependentIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0006066Alcohol metabolic processNASbiological_process
GO:0006069Ethanol oxidationTASbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0017144Drug metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37078489800.92891240450.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0106233553
GSE13712_SHEARUp0.1281157115
GSE13712_STATICUp0.1840489702
GSE19018Up0.2190622039
GSE19899_A1Up0.2429414179
GSE19899_A2Up0.0555981450
PubMed_21979375_A1Up0.1128482891
PubMed_21979375_A2Up0.1325475335
GSE35957Down-0.1439940034
GSE36640Up0.0869156531
GSE54402Down-0.1347842851
GSE9593Up0.3812387711
GSE43922Up0.0269576815
GSE24585Down-0.0208896561
GSE37065Down-0.0727917191
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0747315131

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
FomepizoleDB01213 APRD00985
4-IodopyrazoleDB02721 EXPT02726
N-Cyclopentyl-N-CyclobutylformamideDB04065 EXPT00857

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-132-3pMIMAT0000426MIRT021722MicroarrayFunctional MTI (Weak)17612493
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.