HCSGD entry for SPACA3

1. General information

Official gene symbolSPACA3
Entrez ID124912
Gene full namesperm acrosome associated 3
Other gene symbols1700025M08Rik ALLP17 CT54 LYC3 LYZL3 SLLP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002080Acrosomal membraneIEAcellular_component
GO:0003796Lysozyme activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005764LysosomeIDAcellular_component
GO:0009253Peptidoglycan catabolic processTASbiological_process
GO:0009615Response to virusTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016998Cell wall macromolecule catabolic processIEA TASbiological_process
GO:0030141Secretory granuleIDAcellular_component
GO:0035036Sperm-egg recognitionIEAbiological_process
GO:0042117Monocyte activationTASbiological_process
GO:0043032Positive regulation of macrophage activationTASbiological_process
GO:0050766Positive regulation of phagocytosisTASbiological_process
GO:0050830Defense response to Gram-positive bacteriumTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46723836860.77662786370.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1754941196
GSE13712_SHEARUp0.0127613170
GSE13712_STATICDown-0.0117067294
GSE19018Up0.3726056822
GSE19899_A1Down-0.0063011084
GSE19899_A2Up0.1156540903
PubMed_21979375_A1Down-0.1924757544
PubMed_21979375_A2Down-0.4439703195
GSE35957Up0.0297150832
GSE36640Up0.0033444027
GSE54402Up0.0919361303
GSE9593Up0.0913000389
GSE43922Up0.0422553257
GSE24585Down-0.0755132570
GSE37065Down-0.1902468207
GSE28863_A1Down-0.0654388847
GSE28863_A2Down-0.1170787454
GSE28863_A3Up0.2954879867
GSE28863_A4Up0.1417604184
GSE48662Up0.1284729041

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017609MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.