HCSGD entry for PIGU
1. General information
| Official gene symbol | PIGU |
|---|---|
| Entrez ID | 128869 |
| Gene full name | phosphatidylinositol glycan anchor biosynthesis, class U |
| Other gene symbols | CDC91L1 GAB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003923 | GPI-anchor transamidase activity | IMP | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006506 | GPI anchor biosynthetic process | IDA IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016255 | Attachment of GPI anchor to protein | IMP TAS | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IC | cellular_component |
| GO:0034235 | GPI anchor binding | IMP | molecular_function |
| GO:0042765 | GPI-anchor transamidase complex | IDA | cellular_component |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0046425 | Regulation of JAK-STAT cascade | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9749798070 | 0.0211058128 | 0.9999902473 | 0.2810255943 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1471136560 |
| GSE13712_SHEAR | Down | -0.6019943398 |
| GSE13712_STATIC | Down | -0.1524892250 |
| GSE19018 | Down | -0.1961016957 |
| GSE19899_A1 | Down | -0.6268910407 |
| GSE19899_A2 | Down | -0.4928099595 |
| PubMed_21979375_A1 | Up | 1.2855681519 |
| PubMed_21979375_A2 | Down | -1.1763660905 |
| GSE35957 | Down | -0.7933828229 |
| GSE36640 | Down | -0.0387828634 |
| GSE54402 | Up | 0.1038161954 |
| GSE9593 | Down | -0.4611358542 |
| GSE43922 | Up | 0.0093580400 |
| GSE24585 | Down | -0.4499997024 |
| GSE37065 | Up | 0.0522507190 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.5402800570 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032423 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
