HCSGD entry for COL6A2
1. General information
| Official gene symbol | COL6A2 |
|---|---|
| Entrez ID | 1292 |
| Gene full name | collagen, type VI, alpha 2 |
| Other gene symbols | PP3610 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IDA TAS | cellular_component |
| GO:0005581 | Collagen | IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0009749 | Response to glucose | IEA | biological_process |
| GO:0022617 | Extracellular matrix disassembly | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030574 | Collagen catabolic process | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA IEA ISS | cellular_component |
| GO:0042383 | Sarcolemma | IEA | cellular_component |
| GO:0043234 | Protein complex | IPI | cellular_component |
| GO:0070208 | Protein heterotrimerization | IPI | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0853994187 | 0.0689322062 | 0.6138613159 | 0.4953220311 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6498486750 |
| GSE13712_SHEAR | Down | -0.8537178441 |
| GSE13712_STATIC | Down | -0.3440845511 |
| GSE19018 | Down | -0.0429021985 |
| GSE19899_A1 | Up | 0.1628909466 |
| GSE19899_A2 | Down | -0.2864467496 |
| PubMed_21979375_A1 | Up | 0.4947830560 |
| PubMed_21979375_A2 | Up | 0.9742758263 |
| GSE35957 | Down | -0.8680414109 |
| GSE36640 | Down | -0.2576879153 |
| GSE54402 | Down | -0.2170117546 |
| GSE9593 | Up | 0.1564269555 |
| GSE43922 | Down | -0.0742116264 |
| GSE24585 | Up | 0.5715682848 |
| GSE37065 | Down | -0.4595666280 |
| GSE28863_A1 | Up | 0.7881792292 |
| GSE28863_A2 | Up | 0.8290683087 |
| GSE28863_A3 | Up | 0.5117297584 |
| GSE28863_A4 | Down | -0.2242375251 |
| GSE48662 | Up | 0.7359378960 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022605 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047410 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047536 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3928-3p | MIMAT0018205 | MIRT052889 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
