HCSGD entry for OSR1

1. General information

Official gene symbolOSR1
Entrez ID130497
Gene full nameodd-skipped related 1 (Drosophila)
Other gene symbolsODD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0001655Urogenital system developmentISSbiological_process
GO:0001657Ureteric bud developmentISSbiological_process
GO:0001823Mesonephros developmentISSbiological_process
GO:0002062Chondrocyte differentiationISSbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007507Heart developmentISSbiological_process
GO:0008406Gonad developmentIEAbiological_process
GO:0010628Positive regulation of gene expressionISSbiological_process
GO:0030154Cell differentiationISSbiological_process
GO:0030501Positive regulation of bone mineralizationISSbiological_process
GO:0030857Negative regulation of epithelial cell differentiationISSbiological_process
GO:0035115Embryonic forelimb morphogenesisISSbiological_process
GO:0035116Embryonic hindlimb morphogenesisISSbiological_process
GO:0036023Embryonic skeletal limb joint morphogenesisISSbiological_process
GO:0042474Middle ear morphogenesisISSbiological_process
GO:0042476OdontogenesisISSbiological_process
GO:0042733Embryonic digit morphogenesisISSbiological_process
GO:0043066Negative regulation of apoptotic processISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048389Intermediate mesoderm developmentIEAbiological_process
GO:0048793Pronephros developmentIMPbiological_process
GO:0048863Stem cell differentiationISSbiological_process
GO:0050679Positive regulation of epithelial cell proliferationISSbiological_process
GO:0060021Palate developmentISSbiological_process
GO:0060272Embryonic skeletal joint morphogenesisISSbiological_process
GO:0071300Cellular response to retinoic acidIEAbiological_process
GO:0072075Metanephric mesenchyme developmentISSbiological_process
GO:0072111Cell proliferation involved in kidney developmentISSbiological_process
GO:0072133Metanephric mesenchyme morphogenesisISSbiological_process
GO:0072143Mesangial cell developmentISSbiological_process
GO:0072162Metanephric mesenchymal cell differentiationISSbiological_process
GO:0072166Posterior mesonephric tubule developmentISSbiological_process
GO:0072168Specification of anterior mesonephric tubule identityISSbiological_process
GO:0072169Specification of posterior mesonephric tubule identityISSbiological_process
GO:0072180Mesonephric duct morphogenesisISSbiological_process
GO:0072183Negative regulation of nephron tubule epithelial cell differentiationISSbiological_process
GO:0072184Renal vesicle progenitor cell differentiationISSbiological_process
GO:0072190Ureter urothelium developmentISSbiological_process
GO:0072207Metanephric epithelium developmentISSbiological_process
GO:0072208Metanephric smooth muscle tissue developmentISSbiological_process
GO:0072234Metanephric nephron tubule developmentISSbiological_process
GO:0072239Metanephric glomerulus vasculature developmentISSbiological_process
GO:0072259Metanephric interstitial cell developmentISSbiological_process
GO:0072268Pattern specification involved in metanephros developmentISSbiological_process
GO:0072498Embryonic skeletal joint developmentISSbiological_process
GO:0090094Metanephric cap mesenchymal cell proliferation involved in metanephros developmentISSbiological_process
GO:2000543Positive regulation of gastrulationIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08349657310.00950197180.60877663810.1929594449

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.1433326724
GSE13712_SHEARUp0.1273424330
GSE13712_STATICUp0.0344258599
GSE19018Up1.1831279546
GSE19899_A1Down-1.1888555566
GSE19899_A2Down-0.6123794206
PubMed_21979375_A1Down-3.1915135661
PubMed_21979375_A2Down-1.8608757271
GSE35957Up1.2136934429
GSE36640Down-0.3307013835
GSE54402Down-2.0174358986
GSE9593Up0.8561155350
GSE43922Down-1.2606418277
GSE24585Down-0.0834093968
GSE37065Down-0.5107369957
GSE28863_A1Up0.0044286851
GSE28863_A2Up0.4396025841
GSE28863_A3Up0.1250980175
GSE28863_A4Up0.0781995302
GSE48662Down-0.0267817993

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-93-5pMIMAT0000093MIRT028100SequencingFunctional MTI (Weak)20371350
hsa-miR-21-5pMIMAT0000076MIRT031058MicroarrayFunctional MTI (Weak)18591254
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23841748Here, using quantitative RT-PCR and flow cytometry [fluorescence-activated cell sorting (FACS)] analysis, we show in VPA-treated primary cultures of human adult and fetal kidney significant reinduction of the renal stem/progenitor markers SIX2, OSR1, SALL1, NCAM, and PSA-NCAM
23841748Furthermore, we could demonstrate synergistic effects of VPA and Wnt antagonists on SIX2 and also OSR1 reinduction
Entries Per Page
Displaying Page of