HCSGD entry for COL15A1
1. General information
| Official gene symbol | COL15A1 |
|---|---|
| Entrez ID | 1306 |
| Gene full name | collagen, type XV, alpha 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0005201 | Extracellular matrix structural constituent | IC | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005582 | Collagen type XV | TAS | cellular_component |
| GO:0005604 | Basement membrane | IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IC | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0022617 | Extracellular matrix disassembly | TAS | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030574 | Collagen catabolic process | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0117355382 | 0.0000125565 | 0.2720583627 | 0.0071627451 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3264492148 |
| GSE13712_SHEAR | Down | -0.0878712867 |
| GSE13712_STATIC | Up | 0.0080401765 |
| GSE19018 | Down | -0.7778938733 |
| GSE19899_A1 | Down | -5.8539005435 |
| GSE19899_A2 | Down | -7.3215251073 |
| PubMed_21979375_A1 | Down | -3.2377805544 |
| PubMed_21979375_A2 | Down | -7.6656730275 |
| GSE35957 | Down | -1.3692234396 |
| GSE36640 | Down | -5.4184650938 |
| GSE54402 | Down | -6.5746179537 |
| GSE9593 | Up | 1.1052251056 |
| GSE43922 | Down | -0.0181679023 |
| GSE24585 | Up | 0.1180695061 |
| GSE37065 | Down | -0.9775392811 |
| GSE28863_A1 | Up | 1.3565121628 |
| GSE28863_A2 | Up | 2.9835972506 |
| GSE28863_A3 | Up | 1.0209745489 |
| GSE28863_A4 | Up | 0.1439834827 |
| GSE48662 | Up | 0.3440488073 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT001925 | Luciferase reporter assay//qRT-PCR//Reporter assay;Other | Functional MTI | 18390668 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017996 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029496 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | NA | hsa-miR-29c | 18390668 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
