HCSGD entry for CHCHD4
1. General information
| Official gene symbol | CHCHD4 |
|---|---|
| Entrez ID | 131474 |
| Gene full name | coiled-coil-helix-coiled-coil-helix domain containing 4 |
| Other gene symbols | MIA40 TIMM40 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005758 | Mitochondrial intermembrane space | IDA | cellular_component |
| GO:0006626 | Protein targeting to mitochondrion | TAS | biological_process |
| GO:0015035 | Protein disulfide oxidoreductase activity | IMP | molecular_function |
| GO:0022417 | Protein maturation by protein folding | IMP | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0045041 | Protein import into mitochondrial intermembrane space | IMP | biological_process |
| GO:0051084 | 'de novo' posttranslational protein folding | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2603460659 | 0.1500415562 | 0.9532299624 | 0.7485940485 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3805762916 |
| GSE13712_SHEAR | Up | 0.3356616334 |
| GSE13712_STATIC | Up | 0.2534251494 |
| GSE19018 | Down | -0.4827578564 |
| GSE19899_A1 | Up | 0.0269713158 |
| GSE19899_A2 | Up | 0.8439285978 |
| PubMed_21979375_A1 | Up | 0.6261529153 |
| PubMed_21979375_A2 | Up | 0.7256867917 |
| GSE35957 | Down | -1.0931464043 |
| GSE36640 | Down | -0.1699674433 |
| GSE54402 | Up | 0.1529700656 |
| GSE9593 | Down | -0.8316683734 |
| GSE43922 | Up | 0.2941061324 |
| GSE24585 | Down | -0.2929747900 |
| GSE37065 | Down | -0.0978619934 |
| GSE28863_A1 | Down | -0.1598008971 |
| GSE28863_A2 | Down | -0.2502024164 |
| GSE28863_A3 | Down | -0.3122483636 |
| GSE28863_A4 | Down | -0.1219305207 |
| GSE48662 | Down | -0.0250905985 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043892 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
