HCSGD entry for JMY
1. General information
| Official gene symbol | JMY |
|---|---|
| Entrez ID | 133746 |
| Gene full name | junction mediating and regulatory protein, p53 cofactor |
| Other gene symbols | WHDC1L3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003713 | Transcription coactivator activity | ISS | molecular_function |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | ISS | biological_process |
| GO:0007050 | Cell cycle arrest | ISS | biological_process |
| GO:0031252 | Cell leading edge | IDA | cellular_component |
| GO:0034314 | Arp2/3 complex-mediated actin nucleation | ISS | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | ISS | biological_process |
| GO:0051091 | Positive regulation of sequence-specific DNA binding transcription factor activity | ISS | biological_process |
| GO:0070060 | 'de novo' actin filament nucleation | ISS | biological_process |
| GO:0070358 | Actin polymerization-dependent cell motility | ISS | biological_process |
| GO:0072332 | Intrinsic apoptotic signaling pathway by p53 class mediator | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0014716500 | 0.9679462900 | 0.1035703209 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0134824367 |
| GSE13712_SHEAR | Down | -0.3980060583 |
| GSE13712_STATIC | Down | -0.0812107217 |
| GSE19018 | Up | 0.8193364593 |
| GSE19899_A1 | Up | 0.5405452436 |
| GSE19899_A2 | Up | 0.7063148180 |
| PubMed_21979375_A1 | Up | 1.5257300587 |
| PubMed_21979375_A2 | Up | 1.5637719603 |
| GSE35957 | Up | 0.7018223924 |
| GSE36640 | Up | 1.7477360667 |
| GSE54402 | Up | 0.0119797681 |
| GSE9593 | Up | 0.7123858145 |
| GSE43922 | Up | 0.0634913156 |
| GSE24585 | Up | 0.0216859037 |
| GSE37065 | Up | 0.0575758158 |
| GSE28863_A1 | Up | 1.0418051510 |
| GSE28863_A2 | Up | 1.1672290052 |
| GSE28863_A3 | Up | 0.0996298290 |
| GSE28863_A4 | Down | -0.3648554172 |
| GSE48662 | Up | 0.3199165036 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT005323 | Luciferase reporter assay//qRT-PCR | Functional MTI | 18829576 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT016890 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038309 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
