HCSGD entry for CRABP2
1. General information
| Official gene symbol | CRABP2 |
|---|---|
| Entrez ID | 1382 |
| Gene full name | cellular retinoic acid binding protein 2 |
| Other gene symbols | CRABP-II RBP6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001972 | Retinoic acid binding | IEA | molecular_function |
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005501 | Retinoid binding | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0016918 | Retinal binding | IEA | molecular_function |
| GO:0019841 | Retinol binding | IEA | molecular_function |
| GO:0035115 | Embryonic forelimb morphogenesis | IEA | biological_process |
| GO:0042573 | Retinoic acid metabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1714128187 | 0.0190738878 | 0.8136467640 | 0.2707429570 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4460884669 |
| GSE13712_SHEAR | Down | -0.1903608537 |
| GSE13712_STATIC | Up | 0.0327128144 |
| GSE19018 | Down | -0.0994770097 |
| GSE19899_A1 | Down | -0.2958017247 |
| GSE19899_A2 | Down | -0.8329512622 |
| PubMed_21979375_A1 | Down | -0.1559698579 |
| PubMed_21979375_A2 | Down | -0.8572119021 |
| GSE35957 | Down | -1.8264758118 |
| GSE36640 | Down | -1.2558646105 |
| GSE54402 | Down | -0.4500178372 |
| GSE9593 | Up | 0.3414884742 |
| GSE43922 | Down | -0.3322803817 |
| GSE24585 | Up | 0.7371704495 |
| GSE37065 | Down | -0.1708674839 |
| GSE28863_A1 | Up | 0.4983231629 |
| GSE28863_A2 | Up | 0.6765471885 |
| GSE28863_A3 | Down | -0.3741071576 |
| GSE28863_A4 | Up | 0.0201498412 |
| GSE48662 | Up | 0.0246105381 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019800 | Microarray | Functional MTI (Weak) | 20215506 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20622962 | Downregulated genes included cyclin D2, keratin 8, insulin-like growth factor 2 (IGF2), natriuretic peptide precursor B (NPPB) and cellular retinoic acid binding protein 2 (CRABP2) |
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