HCSGD entry for AMER1
1. General information
| Official gene symbol | AMER1 |
|---|---|
| Entrez ID | 139285 |
| Gene full name | APC membrane recruitment protein 1 |
| Other gene symbols | FAM123B OSCS WTX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005546 | Phosphatidylinositol-4,5-bisphosphate binding | IDA IMP | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0008013 | Beta-catenin binding | IDA | molecular_function |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0060348 | Bone development | IEA | biological_process |
| GO:0060612 | Adipose tissue development | IEA | biological_process |
| GO:0060828 | Regulation of canonical Wnt signaling pathway | IMP | biological_process |
| GO:0072161 | Mesenchymal cell differentiation involved in kidney development | IEA | biological_process |
| GO:0090090 | Negative regulation of canonical Wnt signaling pathway | IMP | biological_process |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7825844953 | 0.2400221344 | 0.9999902473 | 0.9433511423 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0553766226 |
| GSE13712_SHEAR | Down | -0.0755187300 |
| GSE13712_STATIC | Up | 0.0270509909 |
| GSE19018 | Down | -0.2279018255 |
| GSE19899_A1 | Down | -0.0186323120 |
| GSE19899_A2 | Down | -0.1439602994 |
| PubMed_21979375_A1 | Down | -0.0746463544 |
| PubMed_21979375_A2 | Down | -0.3048409711 |
| GSE35957 | Up | 0.1537627736 |
| GSE36640 | Up | 0.1239273232 |
| GSE54402 | Up | 0.1200860849 |
| GSE9593 | Down | -0.1357182571 |
| GSE43922 | Up | 0.0242563732 |
| GSE24585 | Down | -0.7372993127 |
| GSE37065 | Up | 0.0302600272 |
| GSE28863_A1 | Up | 0.3124615632 |
| GSE28863_A2 | Up | 0.4222336903 |
| GSE28863_A3 | Down | -0.5275639211 |
| GSE28863_A4 | Down | -0.0281257009 |
| GSE48662 | Up | 0.0768449254 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT020401 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT042310 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051169 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
