HCSGD entry for SAMD8
1. General information
| Official gene symbol | SAMD8 |
|---|---|
| Entrez ID | 142891 |
| Gene full name | sterile alpha motif domain containing 8 |
| Other gene symbols | SMSr |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0006686 | Sphingomyelin biosynthetic process | NAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0046513 | Ceramide biosynthetic process | IDA | biological_process |
| GO:2000303 | Regulation of ceramide biosynthetic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0027126135 | 0.9964975875 | 0.1401419608 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1834153049 |
| GSE13712_SHEAR | Up | 0.4092366494 |
| GSE13712_STATIC | Up | 0.5059643035 |
| GSE19018 | Up | 0.1460869039 |
| GSE19899_A1 | Up | 0.7065423402 |
| GSE19899_A2 | Up | 1.0786424126 |
| PubMed_21979375_A1 | Up | 0.9405437463 |
| PubMed_21979375_A2 | Up | 0.7737257024 |
| GSE35957 | Up | 0.2833001573 |
| GSE36640 | Up | 0.8764798000 |
| GSE54402 | Up | 0.5900761293 |
| GSE9593 | Up | 0.2521365293 |
| GSE43922 | Up | 0.3627182787 |
| GSE24585 | Up | 0.6266096021 |
| GSE37065 | Up | 0.1627603963 |
| GSE28863_A1 | Up | 0.1200905840 |
| GSE28863_A2 | Up | 0.3350541872 |
| GSE28863_A3 | Down | -0.6221857643 |
| GSE28863_A4 | Up | 0.2106840050 |
| GSE48662 | Up | 0.0412933708 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018718 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028109 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028219 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028307 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031238 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
