HCSGD entry for EIF5AL1


1. General information

Official gene symbolEIF5AL1
Entrez ID143244
Gene full nameeukaryotic translation initiation factor 5A-like 1
Other gene symbolsEIF5AP1 bA342M3.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003746Translation elongation factor activityIEAmolecular_function
GO:0005643Nuclear poreIEAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0006452Translational frameshiftingIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0008612Peptidyl-lysine modification to hypusineIEAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0043022Ribosome bindingIEAmolecular_function
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0045901Positive regulation of translational elongationIEAbiological_process
GO:0045905Positive regulation of translational terminationIEAbiological_process
GO:0051028MRNA transportIEAbiological_process
GO:0051149Positive regulation of muscle cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49841024660.93861013640.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.1581518515
GSE28863_A2Down-0.1589519678
GSE28863_A3Up0.5232723870
GSE28863_A4Up0.1180287183
GSE48662Up0.0504958794

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-100-5pMIMAT0000098MIRT048526CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.