HCSGD entry for HECTD2
1. General information
| Official gene symbol | HECTD2 |
|---|---|
| Entrez ID | 143279 |
| Gene full name | HECT domain containing E3 ubiquitin protein ligase 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IBA IEA | molecular_function |
| GO:0005634 | Nucleus | IBA | cellular_component |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0406792181 | 0.6650424718 | 0.4523692081 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2599784678 |
| GSE13712_SHEAR | Down | -0.1865162647 |
| GSE13712_STATIC | Down | -0.0428351615 |
| GSE19018 | Down | -0.6261301736 |
| GSE19899_A1 | Up | 0.6176271692 |
| GSE19899_A2 | Up | 0.4302408201 |
| PubMed_21979375_A1 | Up | 1.3634575823 |
| PubMed_21979375_A2 | Up | 1.0370535008 |
| GSE35957 | Up | 0.0292142796 |
| GSE36640 | Down | -0.1157315843 |
| GSE54402 | Up | 0.5609686405 |
| GSE9593 | Down | -0.3021548581 |
| GSE43922 | Up | 1.2604164611 |
| GSE24585 | Up | 0.2941279413 |
| GSE37065 | Up | 0.1489166903 |
| GSE28863_A1 | Down | -0.0024754476 |
| GSE28863_A2 | Down | -0.0176427793 |
| GSE28863_A3 | Down | -0.2344956003 |
| GSE28863_A4 | Up | 0.2135095844 |
| GSE48662 | Down | -0.1195250613 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018117 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-340-5p | MIMAT0004692 | MIRT019625 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024205 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT024252 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
