HCSGD entry for PTGR2
1. General information
| Official gene symbol | PTGR2 |
|---|---|
| Entrez ID | 145482 |
| Gene full name | prostaglandin reductase 2 |
| Other gene symbols | PGR2 ZADH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006693 | Prostaglandin metabolic process | IDA | biological_process |
| GO:0008270 | Zinc ion binding | IDA IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0036132 | 13-prostaglandin reductase activity | IEA | molecular_function |
| GO:0047522 | 15-oxoprostaglandin 13-oxidase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2282042780 | 0.2112170206 | 0.9100124678 | 0.8869892965 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1284525341 |
| GSE13712_SHEAR | Up | 0.9187707363 |
| GSE13712_STATIC | Up | 0.3672025970 |
| GSE19018 | Up | 0.2013295208 |
| GSE19899_A1 | Up | 0.0694040313 |
| GSE19899_A2 | Down | -0.2318352547 |
| PubMed_21979375_A1 | Down | -0.4016917213 |
| PubMed_21979375_A2 | Down | -0.8220133356 |
| GSE35957 | Down | -0.1136934529 |
| GSE36640 | Up | 0.4503291110 |
| GSE54402 | Down | -0.2330101383 |
| GSE9593 | Down | -0.0914968389 |
| GSE43922 | Down | -0.0976751531 |
| GSE24585 | Up | 0.0442969983 |
| GSE37065 | Up | 0.0392568329 |
| GSE28863_A1 | Up | 0.1901594282 |
| GSE28863_A2 | Up | 0.3744353508 |
| GSE28863_A3 | Down | -0.6232554031 |
| GSE28863_A4 | Down | -0.0419120161 |
| GSE48662 | Up | 0.0210419825 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Indomethacin | DB00328 | APRD00109 |
| (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID | DB07177 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042357 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
