HCSGD entry for ADRA1D

1. General information

Official gene symbolADRA1D
Entrez ID146
Gene full nameadrenoceptor alpha 1D
Other gene symbolsADRA1 ADRA1A ADRA1R ALPHA1 DAR dJ779E11.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001986Negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressureIEAbiological_process
GO:0001994Norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressureIEAbiological_process
GO:0004937Alpha1-adrenergic receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006259DNA metabolic processTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0008284Positive regulation of cell proliferationTASbiological_process
GO:0071875Adrenergic receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86629732910.62156851560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0830686832
GSE13712_SHEARDown-0.0718719287
GSE13712_STATICUp0.1876040984
GSE19018Down-0.1080233962
GSE19899_A1Down-0.0206129462
GSE19899_A2Up0.0797381721
PubMed_21979375_A1Down-0.2468230786
PubMed_21979375_A2Up0.0459786337
GSE35957Up0.1038412869
GSE36640Up0.0682900914
GSE54402Up0.0577653813
GSE9593Down-0.0030000229
GSE43922Up0.0442042747
GSE24585Down-0.0617013289
GSE37065Up0.0582426929
GSE28863_A1Down-0.2514948395
GSE28863_A2Up0.0924918545
GSE28863_A3Up0.0375631962
GSE28863_A4Down-0.0276582075
GSE48662Down-0.1357199399

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.