HCSGD entry for PIK3R6

1. General information

Official gene symbolPIK3R6
Entrez ID146850
Gene full namephosphoinositide-3-kinase, regulatory subunit 6
Other gene symbolsC17orf38 HsT41028 p84 p84 PIKAP p87(PIKAP) p87PIKAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:00059441-phosphatidylinositol-4-phosphate 3-kinase, class IB complexISScellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006661Phosphatidylinositol biosynthetic processTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayISSbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0016020MembraneISScellular_component
GO:0016310PhosphorylationISSbiological_process
GO:0030168Platelet activationTASbiological_process
GO:0043406Positive regulation of MAP kinase activityISSbiological_process
GO:0043551Regulation of phosphatidylinositol 3-kinase activityISSbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045766Positive regulation of angiogenesisIMPbiological_process
GO:0046854Phosphatidylinositol phosphorylationISSbiological_process
GO:0046934Phosphatidylinositol-4,5-bisphosphate 3-kinase activityISSmolecular_function
GO:00469351-phosphatidylinositol-3-kinase regulator activityISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38832561070.65734151060.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0771695858
GSE13712_SHEARDown-0.0528557811
GSE13712_STATICUp0.1260270923
GSE19018Up0.0538748746
GSE19899_A1Up0.1875024291
GSE19899_A2Up0.2817522269
PubMed_21979375_A1Up0.2661741552
PubMed_21979375_A2Up0.2845542661
GSE35957Down-0.0067201695
GSE36640Down-0.0244345133
GSE54402Up0.1469147072
GSE9593Down-0.1335034234
GSE43922Up0.0727569808
GSE24585Down-0.0194756950
GSE37065Up0.0407765402
GSE28863_A1Down-0.4944103959
GSE28863_A2Down-0.4630447030
GSE28863_A3Up0.3037655126
GSE28863_A4Up0.0623509201
GSE48662Up0.0949721709

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.