HCSGD entry for DACT3
1. General information
| Official gene symbol | DACT3 |
|---|---|
| Entrez ID | 147906 |
| Gene full name | dishevelled-binding antagonist of beta-catenin 3 |
| Other gene symbols | DAPPER3 RRR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005080 | Protein kinase C binding | ISS | molecular_function |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0030178 | Negative regulation of Wnt signaling pathway | IDA | biological_process |
| GO:0030308 | Negative regulation of cell growth | IDA | biological_process |
| GO:0035414 | Negative regulation of catenin import into nucleus | IDA | biological_process |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0051018 | Protein kinase A binding | ISS | molecular_function |
| GO:0070097 | Delta-catenin binding | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5444750313 | 0.5751124159 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1666924866 |
| GSE13712_SHEAR | Down | -0.0013221995 |
| GSE13712_STATIC | Up | 0.1449620028 |
| GSE19018 | Down | -0.1575312519 |
| GSE19899_A1 | Up | 0.0640757472 |
| GSE19899_A2 | Up | 0.0969939842 |
| PubMed_21979375_A1 | Down | -0.5442062944 |
| PubMed_21979375_A2 | Up | 0.0955830786 |
| GSE35957 | Up | 0.2022311703 |
| GSE36640 | Up | 0.9764003519 |
| GSE54402 | Down | -0.1138582200 |
| GSE9593 | Up | 0.0308488889 |
| GSE43922 | Up | 0.0393595223 |
| GSE24585 | Up | 0.1952168904 |
| GSE37065 | Down | -0.0997645626 |
| GSE28863_A1 | Down | -0.2046923679 |
| GSE28863_A2 | Down | -0.2652244159 |
| GSE28863_A3 | Up | 0.1120637601 |
| GSE28863_A4 | Up | 0.0080978979 |
| GSE48662 | Up | 0.2021701708 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-31-5p | MIMAT0000089 | MIRT005875 | Immunoprecipitaion//Luciferase reporter assay//Microarray//qRT-PCR//Western blot | Functional MTI | 21048943 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
