HCSGD entry for RC3H1
1. General information
| Official gene symbol | RC3H1 |
|---|---|
| Entrez ID | 149041 |
| Gene full name | ring finger and CCCH-type domains 1 |
| Other gene symbols | RNF198 ROQUIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000932 | Cytoplasmic mRNA processing body | ISS | cellular_component |
| GO:0000956 | Nuclear-transcribed mRNA catabolic process | ISS | biological_process |
| GO:0002634 | Regulation of germinal center formation | ISS | biological_process |
| GO:0002635 | Negative regulation of germinal center formation | ISS | biological_process |
| GO:0003730 | MRNA 3'-UTR binding | ISS | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010494 | Cytoplasmic stress granule | ISS | cellular_component |
| GO:0010608 | Posttranscriptional regulation of gene expression | ISS | biological_process |
| GO:0016567 | Protein ubiquitination | TAS | biological_process |
| GO:0030889 | Negative regulation of B cell proliferation | ISS | biological_process |
| GO:0033962 | Cytoplasmic mRNA processing body assembly | ISS | biological_process |
| GO:0043488 | Regulation of mRNA stability | ISS | biological_process |
| GO:0045623 | Negative regulation of T-helper cell differentiation | ISS | biological_process |
| GO:0046007 | Negative regulation of activated T cell proliferation | ISS | biological_process |
| GO:0050856 | Regulation of T cell receptor signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0757273926 | 0.8121419893 | 0.5822052570 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0156312165 |
| GSE13712_SHEAR | Up | 0.3133221612 |
| GSE13712_STATIC | Up | 0.3307803065 |
| GSE19018 | Up | 0.0982305349 |
| GSE19899_A1 | Up | 0.0428252619 |
| GSE19899_A2 | Up | 0.2408931489 |
| PubMed_21979375_A1 | Down | -0.2472273189 |
| PubMed_21979375_A2 | Up | 0.3457668915 |
| GSE35957 | Up | 0.7616599812 |
| GSE36640 | Up | 0.1741222497 |
| GSE54402 | Up | 0.1996428575 |
| GSE9593 | Up | 0.1145334602 |
| GSE43922 | Up | 0.0541353866 |
| GSE24585 | Down | -0.1099389770 |
| GSE37065 | Up | 0.2276311743 |
| GSE28863_A1 | Up | 0.3642153633 |
| GSE28863_A2 | Up | 0.5485192466 |
| GSE28863_A3 | Down | -0.8921303386 |
| GSE28863_A4 | Down | -0.2904424103 |
| GSE48662 | Up | 0.2140975524 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037221 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038022 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
