HCSGD entry for BTLA
1. General information
| Official gene symbol | BTLA |
|---|---|
| Entrez ID | 151888 |
| Gene full name | B and T lymphocyte associated |
| Other gene symbols | BTLA1 CD272 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002768 | Immune response-regulating cell surface receptor signaling pathway | IEA | biological_process |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0030889 | Negative regulation of B cell proliferation | IEA | biological_process |
| GO:0031295 | T cell costimulation | TAS | biological_process |
| GO:0046642 | Negative regulation of alpha-beta T cell proliferation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7062483568 | 0.4657334942 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0718519732 |
| GSE13712_SHEAR | Up | 0.0107914715 |
| GSE13712_STATIC | Up | 0.1897283307 |
| GSE19018 | Down | -0.0176195118 |
| GSE19899_A1 | Down | -0.1666012929 |
| GSE19899_A2 | Up | 0.0450953467 |
| PubMed_21979375_A1 | Up | 0.1727907104 |
| PubMed_21979375_A2 | Up | 0.1718314119 |
| GSE35957 | Up | 0.2506755558 |
| GSE36640 | Down | -0.1292902115 |
| GSE54402 | Up | 0.0639745387 |
| GSE9593 | Down | -0.1829053818 |
| GSE43922 | Up | 0.0159187503 |
| GSE24585 | Up | 0.1041430829 |
| GSE37065 | Up | 0.0690126491 |
| GSE28863_A1 | Down | -0.4321748745 |
| GSE28863_A2 | Down | -0.1853583408 |
| GSE28863_A3 | Up | 0.0505252373 |
| GSE28863_A4 | Down | -0.0315168531 |
| GSE48662 | Down | -0.0349699059 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017901 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
