HCSGD entry for CYP2F1


1. General information

Official gene symbolCYP2F1
Entrez ID1572
Gene full namecytochrome P450, family 2, subfamily F, polypeptide 1
Other gene symbolsC2F1 CYP2F
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004497Monooxygenase activityIEA TASmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0009636Response to toxic substanceIEAbiological_process
GO:0016705Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenIEAmolecular_function
GO:0016712Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenIDAmolecular_function
GO:0018931Naphthalene metabolic processIDAbiological_process
GO:0018979Trichloroethylene metabolic processIEAbiological_process
GO:0019825Oxygen bindingIEAmolecular_function
GO:0020037Heme bindingIEAmolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0070330Aromatase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34636799510.78078577560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1298800066
GSE13712_SHEARUp0.0781769397
GSE13712_STATICUp0.1684779106
GSE19018Up0.2139757017
GSE19899_A1Up0.1236455765
GSE19899_A2Down-0.1584428162
PubMed_21979375_A1Down-0.0230769607
PubMed_21979375_A2Down-0.0079326671
GSE35957Up0.0880211506
GSE36640Down-0.0863372841
GSE54402Up0.0019024862
GSE9593Down-0.0218272901
GSE43922Down-0.0449205930
GSE24585Up0.1036237248
GSE37065Up0.0447865514
GSE28863_A1Up0.0644695003
GSE28863_A2Up0.0579160623
GSE28863_A3Up0.5541223469
GSE28863_A4Up0.0089495604
GSE48662Down-0.0512390041

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017971MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT029482MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.