HCSGD entry for PRUNE2
1. General information
| Official gene symbol | PRUNE2 |
|---|---|
| Entrez ID | 158471 |
| Gene full name | prune homolog 2 (Drosophila) |
| Other gene symbols | A214N16.3 BMCC1 BNIPXL C9orf65 KIAA0367 RP11-58J3.2 bA214N16.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016462 | Pyrophosphatase activity | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0743563162 | 0.0318731127 | 0.5786908930 | 0.3355728800 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0068717902 |
| GSE13712_SHEAR | Up | 0.3375796263 |
| GSE13712_STATIC | Up | 0.5273440109 |
| GSE19018 | Down | -0.5193215742 |
| GSE19899_A1 | Up | 0.0828448260 |
| GSE19899_A2 | Down | -1.5781353711 |
| PubMed_21979375_A1 | Down | -1.0838587589 |
| PubMed_21979375_A2 | Down | -0.4420134230 |
| GSE35957 | Down | -0.7195315668 |
| GSE36640 | Up | 1.7404787615 |
| GSE54402 | Down | -0.6929264671 |
| GSE9593 | Up | 1.4162404608 |
| GSE43922 | Down | -0.9772986591 |
| GSE24585 | Up | 1.1365392360 |
| GSE37065 | Down | -0.2361038063 |
| GSE28863_A1 | Up | 0.1289318551 |
| GSE28863_A2 | Up | 0.9048280035 |
| GSE28863_A3 | Down | -0.1478154466 |
| GSE28863_A4 | Down | -0.2857814667 |
| GSE48662 | Down | -0.3484664998 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020306 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026082 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028167 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031283 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039197 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
