HCSGD entry for DACH1
1. General information
| Official gene symbol | DACH1 |
|---|---|
| Entrez ID | 1602 |
| Gene full name | dachshund homolog 1 (Drosophila) |
| Other gene symbols | DACH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0001075 | RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly | IEA | molecular_function |
| GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | IDA | molecular_function |
| GO:0001967 | Suckling behavior | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007585 | Respiratory gaseous exchange | IEA | biological_process |
| GO:0008283 | Cell proliferation | IEA | biological_process |
| GO:0010944 | Negative regulation of transcription by competitive promoter binding | IMP | biological_process |
| GO:0030336 | Negative regulation of cell migration | IDA | biological_process |
| GO:0046545 | Development of primary female sexual characteristics | IEA | biological_process |
| GO:0048147 | Negative regulation of fibroblast proliferation | IEA | biological_process |
| GO:0060244 | Negative regulation of cell proliferation involved in contact inhibition | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7825576726 | 0.0427834391 | 0.9999902473 | 0.3889820035 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1108653103 |
| GSE13712_SHEAR | Down | -1.3155528885 |
| GSE13712_STATIC | Down | -2.5311824109 |
| GSE19018 | Down | -0.5284126406 |
| GSE19899_A1 | Up | 0.1865395430 |
| GSE19899_A2 | Down | -0.7695477670 |
| PubMed_21979375_A1 | Up | 0.0949134721 |
| PubMed_21979375_A2 | Up | 0.2995341489 |
| GSE35957 | Up | 0.0930800463 |
| GSE36640 | Up | 0.7597861020 |
| GSE54402 | Up | 0.1481753163 |
| GSE9593 | Down | -0.0971910122 |
| GSE43922 | Up | 0.0137526095 |
| GSE24585 | Down | -0.7619795095 |
| GSE37065 | Down | -0.0152539464 |
| GSE28863_A1 | Down | -0.0616853758 |
| GSE28863_A2 | Down | -0.1238427276 |
| GSE28863_A3 | Up | 0.0909893045 |
| GSE28863_A4 | Up | 0.0694296129 |
| GSE48662 | Up | 0.1197309094 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018559 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
