HCSGD entry for SYNE3


1. General information

Official gene symbolSYNE3
Entrez ID161176
Gene full namespectrin repeat containing, nuclear envelope family member 3
Other gene symbolsC14orf49 NET53 Nesp3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005635Nuclear envelopeIDAcellular_component
GO:0005640Nuclear outer membraneIEAcellular_component
GO:0007010Cytoskeleton organizationIMPbiological_process
GO:0008360Regulation of cell shapeIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0034993SUN-KASH complexIDAcellular_component
GO:0051015Actin filament bindingIMPmolecular_function
GO:0090150Establishment of protein localization to membraneIDAbiological_process
GO:0090286Cytoskeletal anchoring at nuclear membraneIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22768946470.48379435810.90964280081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1729709958
GSE13712_SHEARDown-0.1191504944
GSE13712_STATICDown-0.1175994121
GSE19018Up0.1718262252
GSE19899_A1Up0.1177504264
GSE19899_A2Up0.0002105023
PubMed_21979375_A1Down-0.5548782886
PubMed_21979375_A2Up0.0927078528
GSE35957Down-0.2692937001
GSE36640Up0.1176096619
GSE54402Down-0.1046684015
GSE9593Up0.1512200115
GSE43922Down-0.7355728069
GSE24585Down-0.0653575389
GSE37065Down-0.3285168092
GSE28863_A1Up0.8312046616
GSE28863_A2Up0.6670228759
GSE28863_A3Down-0.0879213344
GSE28863_A4Up0.1717353776
GSE48662Up0.2431620776

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018850MicroarrayFunctional MTI (Weak)18185580
hsa-miR-132-3pMIMAT0000426MIRT021781MicroarrayFunctional MTI (Weak)17612493
hsa-miR-328-3pMIMAT0000752MIRT043818CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.