HCSGD entry for ECI1
1. General information
| Official gene symbol | ECI1 |
|---|---|
| Entrez ID | 1632 |
| Gene full name | enoyl-CoA delta isomerase 1 |
| Other gene symbols | DCI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004165 | Dodecenoyl-CoA delta-isomerase activity | IEA NAS TAS | molecular_function |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | NAS TAS | cellular_component |
| GO:0006635 | Fatty acid beta-oxidation | IEA NAS TAS | biological_process |
| GO:0016860 | Intramolecular oxidoreductase activity | TAS | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1887277459 | 0.3214467915 | 0.8468137719 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1467124270 |
| GSE13712_SHEAR | Up | 0.3273061143 |
| GSE13712_STATIC | Up | 0.4008049893 |
| GSE19018 | Up | 0.3499294171 |
| GSE19899_A1 | Down | -0.3938915997 |
| GSE19899_A2 | Up | 0.4855458386 |
| PubMed_21979375_A1 | Up | 1.2267056016 |
| PubMed_21979375_A2 | Up | 0.0830305269 |
| GSE35957 | Down | -0.7961754926 |
| GSE36640 | Up | 0.1515709759 |
| GSE54402 | Down | -0.2584029845 |
| GSE9593 | Down | -0.1769097263 |
| GSE43922 | Down | -0.0378279419 |
| GSE24585 | Up | 0.4818957804 |
| GSE37065 | Down | -0.3134012285 |
| GSE28863_A1 | Down | -0.0945246145 |
| GSE28863_A2 | Down | -0.2560540834 |
| GSE28863_A3 | Up | 0.1437479788 |
| GSE28863_A4 | Up | 0.1721046554 |
| GSE48662 | Down | -0.0100329576 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020571 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050587 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 11909691 | Iron is released from hemoglobin or its derivatives in a nonprotein-bound, desferrioxamine-chelatable form (DCI) in a number of conditions in which the erythrocytes are subjected to oxidative stress |
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