HCSGD entry for IDO2
1. General information
| Official gene symbol | IDO2 |
|---|---|
| Entrez ID | 169355 |
| Gene full name | indoleamine 2,3-dioxygenase 2 |
| Other gene symbols | INDOL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004833 | Tryptophan 2,3-dioxygenase activity | EXP | molecular_function |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006569 | Tryptophan catabolic process | TAS | biological_process |
| GO:0019441 | Tryptophan catabolic process to kynurenine | IDA IEA ISS | biological_process |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0033754 | Indoleamine 2,3-dioxygenase activity | IDA IEA ISS | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6314933969 | 0.8129121956 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0947345962 |
| GSE13712_SHEAR | Down | -0.2146812449 |
| GSE13712_STATIC | Down | -0.1320529025 |
| GSE19018 | Down | -0.1415680768 |
| GSE19899_A1 | Down | -0.0008546317 |
| GSE19899_A2 | Up | 0.0941523402 |
| PubMed_21979375_A1 | Up | 0.0651165968 |
| PubMed_21979375_A2 | Up | 0.1052438177 |
| GSE35957 | Up | 0.1014571709 |
| GSE36640 | Up | 0.2631262290 |
| GSE54402 | Up | 0.0137809641 |
| GSE9593 | Up | 0.0910875779 |
| GSE43922 | Up | 0.0102772282 |
| GSE24585 | Up | 0.1265966898 |
| GSE37065 | Up | 0.0077079326 |
| GSE28863_A1 | Up | 0.0993309711 |
| GSE28863_A2 | Down | -0.1212156601 |
| GSE28863_A3 | Up | 0.2565817051 |
| GSE28863_A4 | Down | -0.0158928452 |
| GSE48662 | Down | -0.0509260494 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
