HCSGD entry for DLX6


1. General information

Official gene symbolDLX6
Entrez ID1750
Gene full namedistal-less homeobox 6
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000976Transcription regulatory region sequence-specific DNA bindingIEAmolecular_function
GO:0001501Skeletal system developmentTASbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0007399Nervous system developmentTASbiological_process
GO:0030326Embryonic limb morphogenesisIEAbiological_process
GO:0030855Epithelial cell differentiationIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0048646Anatomical structure formation involved in morphogenesisIEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0060021Palate developmentIEAbiological_process
GO:0060322Head developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80499756090.43544751720.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0548513284
GSE13712_SHEARDown-0.0097973459
GSE13712_STATICUp0.1321853229
GSE19018Down-0.0743519488
GSE19899_A1Up0.0142127165
GSE19899_A2Down-0.0270293072
PubMed_21979375_A1Down-0.2148279089
PubMed_21979375_A2Down-0.1403193527
GSE35957Down-0.6924448787
GSE36640Down-0.0208011806
GSE54402Up0.0029075204
GSE9593Down-0.0451204080
GSE43922Up0.1695389153
GSE24585Up0.3794462187
GSE37065Down-0.1591619455
GSE28863_A1Down-0.0090460087
GSE28863_A2Up0.0368244112
GSE28863_A3Up0.1711179321
GSE28863_A4Down-0.0744611749
GSE48662Down-0.2768181440

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019311MicroarrayFunctional MTI (Weak)17612493
hsa-miR-92a-3pMIMAT0000092MIRT049253CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.