HCSGD entry for DOK1


1. General information

Official gene symbolDOK1
Entrez ID1796
Gene full namedocking protein 1, 62kDa (downstream of tyrosine kinase 1)
Other gene symbolsP62DOK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005057Receptor signaling protein activityIEAmolecular_function
GO:0005158Insulin receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0007169Transmembrane receptor protein tyrosine kinase signaling pathwayTASbiological_process
GO:0007265Ras protein signal transductionIEAbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82607549110.07176810150.99999024730.5049092800

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0372605171
GSE13712_SHEARDown-0.3460060094
GSE13712_STATICDown-0.1993665336
GSE19018Up0.3236234999
GSE19899_A1Up0.0365120302
GSE19899_A2Down-0.5360124737
PubMed_21979375_A1Down-0.7649588313
PubMed_21979375_A2Down-0.7103521656
GSE35957Down-0.5974480872
GSE36640Up0.3504488256
GSE54402Down-0.0953597965
GSE9593Up0.7892050279
GSE43922Down-0.1137280724
GSE24585Down-0.2146500058
GSE37065Up0.0510123067
GSE28863_A1Down-0.4328417981
GSE28863_A2Up0.2110224263
GSE28863_A3Down-0.1636730138
GSE28863_A4Down-0.1767804461
GSE48662Up0.1295434696

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.