HCSGD entry for DSCAM

1. General information

Official gene symbolDSCAM
Entrez ID1826
Gene full nameDown syndrome cell adhesion molecule
Other gene symbolsCHD2-42 CHD2-52
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005886Plasma membraneISS TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007162Negative regulation of cell adhesionISSbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0016020MembraneTAScellular_component
GO:0030424AxonISScellular_component
GO:0030426Growth coneISScellular_component
GO:0042327Positive regulation of phosphorylationIDAbiological_process
GO:0048813Dendrite morphogenesisIEAbiological_process
GO:0048842Positive regulation of axon extension involved in axon guidanceIDAbiological_process
GO:0060060Post-embryonic retina morphogenesis in camera-type eyeIEAbiological_process
GO:0070593Dendrite self-avoidanceISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68509057790.94013211120.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0058325941
GSE13712_SHEARUp0.0118586801
GSE13712_STATICDown-0.1759291273
GSE19018Up0.2209612033
GSE19899_A1Up0.1190253051
GSE19899_A2Up0.0282712495
PubMed_21979375_A1Up0.1942338383
PubMed_21979375_A2Up0.0384716386
GSE35957Up0.0972678730
GSE36640Up0.0397656407
GSE54402Up0.0965517059
GSE9593Up0.0525873782
GSE43922Up0.0237090944
GSE24585Up0.0924287248
GSE37065Down-0.0291257141
GSE28863_A1Down-0.0379651561
GSE28863_A2Down-0.0144489597
GSE28863_A3Up0.1472829795
GSE28863_A4Up0.0307076173
GSE48662Down-0.0001143998

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.