HCSGD entry for DVL3
1. General information
| Official gene symbol | DVL3 |
|---|---|
| Entrez ID | 1857 |
| Gene full name | dishevelled segment polarity protein 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001934 | Positive regulation of protein phosphorylation | IMP | biological_process |
| GO:0002020 | Protease binding | IPI | molecular_function |
| GO:0003148 | Outflow tract septum morphogenesis | IBA IEA | biological_process |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005102 | Receptor binding | IEA IPI | molecular_function |
| GO:0005109 | Frizzled binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005938 | Cell cortex | IBA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0008013 | Beta-catenin binding | IDA | molecular_function |
| GO:0016055 | Wnt signaling pathway | IDA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0035567 | Non-canonical Wnt signaling pathway | IMP | biological_process |
| GO:0038031 | Non-canonical Wnt signaling pathway via JNK cascade | IEA ISS | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0043507 | Positive regulation of JUN kinase activity | IMP | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IDA | molecular_function |
| GO:0060026 | Convergent extension | IBA | biological_process |
| GO:0060070 | Canonical Wnt signaling pathway | IDA IMP | biological_process |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | IDA | biological_process |
| GO:0090103 | Cochlea morphogenesis | IBA IEA | biological_process |
| GO:0090179 | Planar cell polarity pathway involved in neural tube closure | IBA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8061455834 | 0.1885810228 | 0.9999902473 | 0.8417230965 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1945173481 |
| GSE13712_SHEAR | Down | -0.1334862693 |
| GSE13712_STATIC | Up | 0.1057849002 |
| GSE19018 | Down | -0.2072000147 |
| GSE19899_A1 | Down | -0.1625618585 |
| GSE19899_A2 | Down | -0.1917128128 |
| PubMed_21979375_A1 | Down | -0.3275236643 |
| PubMed_21979375_A2 | Up | 0.3005690022 |
| GSE35957 | Up | 0.0029559683 |
| GSE36640 | Up | 0.5604556784 |
| GSE54402 | Up | 0.0609903095 |
| GSE9593 | Up | 0.0752291977 |
| GSE43922 | Up | 0.0006173588 |
| GSE24585 | Down | -0.0549234429 |
| GSE37065 | Down | -0.2464765694 |
| GSE28863_A1 | Up | 0.2616623213 |
| GSE28863_A2 | Up | 0.0980675912 |
| GSE28863_A3 | Down | -0.1665727098 |
| GSE28863_A4 | Down | -0.3463976708 |
| GSE48662 | Up | 0.0516071450 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030326 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039825 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044424 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048809 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050752 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
