HCSGD entry for E2F5
1. General information
| Official gene symbol | E2F5 |
|---|---|
| Entrez ID | 1875 |
| Gene full name | E2F transcription factor 5, p130-binding |
| Other gene symbols | E2F-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0009887 | Organ morphogenesis | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0051726 | Regulation of cell cycle | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9785438509 | 0.0473778808 | 0.9999902473 | 0.4083278324 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0352694794 |
| GSE13712_SHEAR | Down | -0.0706475546 |
| GSE13712_STATIC | Down | -0.1068176284 |
| GSE19018 | Up | 0.0717984974 |
| GSE19899_A1 | Down | -0.1040586453 |
| GSE19899_A2 | Up | 0.1196987711 |
| PubMed_21979375_A1 | Up | 0.4366566635 |
| PubMed_21979375_A2 | Down | -0.3501653236 |
| GSE35957 | Down | -0.2435445329 |
| GSE36640 | Down | -0.2321216886 |
| GSE54402 | Up | 0.1323066474 |
| GSE9593 | Down | -0.3337188863 |
| GSE43922 | Down | -0.0035134025 |
| GSE24585 | Down | -0.8687909905 |
| GSE37065 | Down | -0.0725295093 |
| GSE28863_A1 | Down | -0.2250463820 |
| GSE28863_A2 | Down | -0.3952611280 |
| GSE28863_A3 | Down | -0.0524992173 |
| GSE28863_A4 | Down | -0.0666862715 |
| GSE48662 | Down | -0.3158831101 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT000750 | Microarray | Functional MTI (Weak) | 19461653 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002917 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-205-5p | MIMAT0000266 | MIRT003321 | Reporter assay | Functional MTI | 21454583 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT003833 | Microarray | Functional MTI (Weak) | 17699775 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT004134 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017999 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT023808 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043926 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
