HCSGD entry for PHC2


1. General information

Official gene symbolPHC2
Entrez ID1912
Gene full namepolyhomeotic homolog 2 (Drosophila)
Other gene symbolsEDR2 HPH2 PH2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0031519PcG protein complexIDAcellular_component
GO:0035102PRC1 complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12173249500.78444776030.71329496881.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1630626822
GSE13712_SHEARUp0.0036449822
GSE13712_STATICUp0.0265763686
GSE19018Down-0.1872157135
GSE19899_A1Up0.2427402954
GSE19899_A2Up0.4843775578
PubMed_21979375_A1Up0.7226773349
PubMed_21979375_A2Up0.5948221713
GSE35957Down-0.2808990776
GSE36640Down-0.3206427044
GSE54402Up0.9230346913
GSE9593Down-0.1726023845
GSE43922Up0.4933435832
GSE24585Down-0.1649078007
GSE37065Down-0.0604945601
GSE28863_A1Up0.0903058055
GSE28863_A2Up0.2378766240
GSE28863_A3Down-0.0376130910
GSE28863_A4Down-0.1358788262
GSE48662Down-0.2828654273

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001526pSILAC//ProteomicsFunctional MTI (Weak)18668040
hsa-miR-155-5pMIMAT0000646MIRT001526Reporter assay;OtherFunctional MTI20584899
hsa-miR-373-3pMIMAT0000726MIRT002500Microarray//Microarray;OtherFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT022596Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-7-5pMIMAT0000252MIRT025770MicroarrayFunctional MTI (Weak)19073608
hsa-miR-192-5pMIMAT0000222MIRT026403MicroarrayFunctional MTI (Weak)19074876
hsa-miR-744-5pMIMAT0004945MIRT037714CLASHFunctional MTI (Weak)23622248
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-373-3pMIMAT0000726NAhsa-miR-37315685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.