HCSGD entry for ELF3


1. General information

Official gene symbolELF3
Entrez ID1999
Gene full nameE74-like factor 3 (ets domain transcription factor, epithelial-specific )
Other gene symbolsEPR-1 ERT ESE-1 ESX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001824Blastocyst developmentIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA NAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006954Inflammatory responseIEPbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008544Epidermis developmentNASbiological_process
GO:0030198Extracellular matrix organizationIEAbiological_process
GO:0030855Epithelial cell differentiationIEPbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0060056Mammary gland involutionISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59622579690.81299820680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0060759156
GSE13712_SHEARDown-0.1269085783
GSE13712_STATICUp0.0273045172
GSE19018Up0.0966882843
GSE19899_A1Down-0.0058391972
GSE19899_A2Up0.1189890722
PubMed_21979375_A1Up0.2007567020
PubMed_21979375_A2Down-0.0291330608
GSE35957Up0.1932532052
GSE36640Down-0.0474044208
GSE54402Down-0.4351503835
GSE9593Down-0.0469238218
GSE43922Up0.0177095325
GSE24585Down-0.0163002910
GSE37065Up0.2857835040
GSE28863_A1Up0.0784871655
GSE28863_A2Up0.0423451541
GSE28863_A3Up0.2010517278
GSE28863_A4Up0.2559650345
GSE48662Down-0.0428602306

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-9-5pMIMAT0000441MIRT021421MicroarrayFunctional MTI (Weak)17612493
hsa-miR-124-3pMIMAT0000422MIRT023041MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.