HCSGD entry for TET3
1. General information
| Official gene symbol | TET3 |
|---|---|
| Entrez ID | 200424 |
| Gene full name | tet methylcytosine dioxygenase 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001939 | Female pronucleus | IEA | cellular_component |
| GO:0001940 | Male pronucleus | ISS | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0006493 | Protein O-linked glycosylation | IMP | biological_process |
| GO:0044727 | DNA demethylation of male pronucleus | ISS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0070579 | Methylcytosine dioxygenase activity | ISS | molecular_function |
| GO:0080111 | DNA demethylation | ISS | biological_process |
| GO:0080182 | Histone H3-K4 trimethylation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3572869078 | 0.5857582767 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0860562277 |
| GSE13712_SHEAR | Up | 0.4251404001 |
| GSE13712_STATIC | Down | -0.1874630727 |
| GSE19018 | Down | -0.1244302083 |
| GSE19899_A1 | Up | 0.1415647272 |
| GSE19899_A2 | Down | -0.2564736822 |
| PubMed_21979375_A1 | Up | 0.7130282570 |
| PubMed_21979375_A2 | Down | -0.0167615772 |
| GSE35957 | Down | -0.0055758691 |
| GSE36640 | Down | -0.5205822352 |
| GSE54402 | Up | 0.1441965137 |
| GSE9593 | Down | -0.1723928036 |
| GSE43922 | Up | 0.2333888648 |
| GSE24585 | Down | -0.5059887963 |
| GSE37065 | Up | 0.1690468834 |
| GSE28863_A1 | Up | 0.1435394624 |
| GSE28863_A2 | Up | 0.4878047118 |
| GSE28863_A3 | Up | 0.0501864148 |
| GSE28863_A4 | Up | 0.0126999106 |
| GSE48662 | Up | 0.0263104881 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-548b-3p | MIMAT0003254 | MIRT016232 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027815 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030262 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
