HCSGD entry for FBXO45
1. General information
| Official gene symbol | FBXO45 |
|---|---|
| Entrez ID | 200933 |
| Gene full name | F-box protein 45 |
| Other gene symbols | Fbx45 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006974 | Cellular response to DNA damage stimulus | IDA | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IDA IEA ISS | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0042734 | Presynaptic membrane | IEA | cellular_component |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | IEA ISS | biological_process |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0542586984 | 0.5638183998 | 0.5084169455 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0467877035 |
| GSE13712_SHEAR | Up | 0.3985252417 |
| GSE13712_STATIC | Up | 0.2178779821 |
| GSE19018 | Down | -0.3429287934 |
| GSE19899_A1 | Up | 0.5320998132 |
| GSE19899_A2 | Up | 0.6517455952 |
| PubMed_21979375_A1 | Up | 0.7112842756 |
| PubMed_21979375_A2 | Up | 0.5985136436 |
| GSE35957 | Down | -0.6400568466 |
| GSE36640 | Down | -0.9157397178 |
| GSE54402 | Up | 0.7988721581 |
| GSE9593 | Down | -0.4789229935 |
| GSE43922 | Up | 0.4921789004 |
| GSE24585 | Down | -0.2391421317 |
| GSE37065 | Down | -0.0633022800 |
| GSE28863_A1 | Up | 0.1962037536 |
| GSE28863_A2 | Up | 0.3763437460 |
| GSE28863_A3 | Up | 0.1542180339 |
| GSE28863_A4 | Down | -0.1259552037 |
| GSE48662 | - | - |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023967 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039138 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049278 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
